中国科学院化学研究所机构知识库
Advanced  
ICCAS OpenIR  > 高分子物理与化学实验室  > 期刊论文
题名: Benzoic-Imine-Based Physiological-pH-Responsive Materials for Biomedical Applications
作者: Qu, Xiaozhong1, 2; Yang, Zhenzhong1
关键词: benzoic imines ; biomedical applications ; drug delivery ; polymers ; responsive materials
刊名: CHEMISTRY-AN ASIAN JOURNAL
发表日期: 2016-10-01
卷: 11, 期:19, 页:2633-2641
收录类别: SCI
英文摘要: The benzoic imine is a dynamic covalent bond, which is stable around neutral pH value (ca. 7.4), but starts to hydrolyze at the extracellular pH value of solid tumors (ca. 6.5) and rapidly disintegrates at endosome and lysosome pH values (ca. 4.5-6.5). This characteristic is promising for the construction of physiological-pH-responsive materials, such as polymeric micelles, nanoparticles, and hydrogels for pharmaceutical and tissue-engineering applications. This Focus Review summarizes recent progress in the design and synthesis of pH-sensitive materials that contain the benzoic imine bond with biomedical objectives.
语种: 英语
内容类型: 期刊论文
URI标识: http://ir.iccas.ac.cn/handle/121111/35115
Appears in Collections:高分子物理与化学实验室_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Chinese Acad Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Coll Mat Sci & Optoelect Technol, Beijing 100049, Peoples R China
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Qu, Xiaozhong]'s Articles
[Yang, Zhenzhong]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Qu, Xiaozhong]‘s Articles
[Yang, Zhenzhong]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  中国科学院化学研究所 - Feedback
Powered by CSpace